Alpha-Gal What Is

Alpha-Gal syndrome, also known as red meat allergy or mammalian meat allergy, is a food allergy to a sugar molecule called alpha-gal. Alpha-gal is found in red meat, such as beef, pork, lamb, and venison, as well as in some other mammalian products, such as milk, cheese, and gelatin.

Alpha-Gal syndrome is caused by a bite from a tick of the genus Amblyomma, which transmits a carbohydrate molecule called alpha-galactose. When a person who is bitten by an Amblyomma tick later consumes red meat, the alpha-galactose molecule binds to antibodies produced by the immune system, which can trigger an allergic reaction.

Symptoms of alpha-Gal syndrome can include:

* Hives

* Swelling

* Difficulty breathing

* Abdominal pain

* Nausea

* Vomiting

* Diarrhea

Alpha-Gal syndrome can be diagnosed with a blood test that checks for antibodies to alpha-galactose. Treatment for alpha-Gal syndrome involves avoiding red meat and other mammalian products. There is no cure for alpha-Gal syndrome, but it can be managed by avoiding trigger foods.