Are skin lesions of chickenpox a sign infection?

Yes, skin lesions of chickenpox are a sign of infection with the varicella-zoster virus. The virus causes an itchy rash that typically starts on the chest, back, and face and then spreads to the rest of the body. The rash consists of small, fluid-filled blisters that eventually crust over and form scabs. Chickenpox is a highly contagious disease, and it is spread through contact with an infected person's respiratory droplets or through direct contact with the rash.