Itching (Pruritus): Common Causes and When to See a Doctor

Frequent Causes

  • Xerosis (dry skin): Most common, especially in winter/elderly.
  • Insect bites/stings: Local histamine reaction.
  • Allergic/contact dermatitis: Eczema, hives, nickel, fragrance.
  • Infections: Fungal (tinea), bacterial (impetigo), viral (varicella).
  • Systemic disease: Cholestasis, uremia, thyroid disorders, lymphoma, iron deficiency.
  • Medications: Opioids, ACE inhibitors, statins.
  • Neuropathic: Brachioradial pruritus, notalgia paresthetica.

Red Flags

Generalized itch without rash, weight loss, night sweats, jaundice, or lymphadenopathy → urgent evaluation.

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