Can retention of urine cause sepsis?

Urinary tract infections (UTIs), including those caused by urine retention, can lead to sepsis if left untreated or if the infection spreads to the bloodstream. Sepsis is a life-threatening condition that occurs when the body's immune system overreacts to an infection, leading to inflammation and tissue damage.

Here's how urine retention can contribute to sepsis:

1. Urinary Stasis: When urine is not emptied regularly from the bladder, it can lead to urinary stasis, creating a favorable environment for bacteria to multiply and cause infection.

2. Increased Pressure: Urine retention can cause increased pressure within the bladder and urinary tract, compromising blood flow and oxygen supply to the tissues, making them more susceptible to infection.

3. Vesicoureteral Reflux: Urine retention can lead to vesicoureteral reflux, a condition in which urine flows back into the ureters and kidneys. This can introduce bacteria into the upper urinary tract, increasing the risk of infection and potentially leading to sepsis.

4. Impaired Immune Response: Chronic urine retention can impair the immune system's ability to fight off infections effectively, making individuals more vulnerable to severe UTIs and the development of sepsis.

5. Underlying Health Conditions: People with underlying health conditions, such as diabetes, immunosuppression, or neurological disorders affecting bladder function, may be at higher risk of developing severe UTIs and sepsis if they experience urine retention.

It's important to note that not all cases of urine retention lead to sepsis. However, prompt diagnosis and treatment of UTIs, including addressing any underlying causes of urine retention, are crucial to preventing the progression of infection and reducing the risk of developing sepsis.