Penicillin VK for Sinus Infections: Effectiveness and Usage

Penicillin VK (penicillin V potassium) can treat some bacterial sinus infections but has limitations:

• Narrower spectrum; many H. influenzae and M. catarrhalis produce β-lactamase (resistant).
• Not recommended as first-line for acute bacterial sinusitis in most guidelines.
• May be used for streptococcal infections or if culture shows susceptibility.

If prescribed, take the full course (usually 10 days) even if symptoms improve. Side effects: nausea, vomiting, diarrhea, rash. Seek emergency care for anaphylaxis (swelling, breathing difficulty).