Regeneration vs. Fibrosis: Understanding Tissue Repair
Regeneration and fibrosis are distinct tissue repair processes.
Regeneration
- Damaged tissue replaced with same-type tissue via stem/progenitor cell proliferation.
- Rapid, complete; restores normal structure and function.
Fibrosis (Scarring)
- Damaged tissue replaced with fibrous connective tissue (collagen) via fibroblast proliferation.
- Slower, less complete; scar tissue may not fully restore function.
Both can occur simultaneously or sequentially. The balance determines repair outcome, influenced by injury severity, tissue type, and individual health.
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