Decoding Prescription Sig Codes: "Sig 2 Puff QID 30 Days" Explained

Prescription directions (Sig) use Latin abbreviations. "Sig 2 puff QID 30 days" translates to:

Take 2 puffs by inhalation four times daily for 30 days.

Breakdown

Common Sig Abbreviations

  • QD / qd / daily = once daily
  • BID / bid = twice daily (bis in die)
  • TID / tid = three times daily (ter in die)
  • QID / qid = four times daily (quater in die)
  • QHS / qhs = at bedtime (quaque hora somni)
  • PRN / prn = as needed (pro re nata)
  • AC / ac = before meals (ante cibum)
  • PC / pc = after meals (post cibum)
  • PO / po = by mouth (per os)
  • SL / sl = sublingual
  • IV / IV = intravenous
  • IM / im = intramuscular
  • SC / SQ / subq = subcutaneous
  • INH / inh = inhalation
  • TOP / top = topical

Safety Note

  • The Joint Commission "Do Not Use" list: Avoid QD (use "daily"), QOD (use "every other day"), trailing zeros (1.0 mg), leading decimals (.5 mg → 0.5 mg), MS/MSO4/MgSO4 (write "morphine sulfate," "magnesium sulfate").
  • E-prescribing and structured sig fields reduce ambiguity.
  • Patients should receive plain-language labels: "Inhale 2 puffs 4 times a day for 30 days."

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ComponentAbbreviationLatin OriginMeaning
Dose2 puff—Two actuations/inhalations
FrequencyQIDquater in dieFour times a day (~every 6 hours)
Duration30 days—Thirty-day supply